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Bioelectronics

Organic bioelectronics comprises the development and study of organic-based devices that operate as transducers between the signals and functions of biology and those of conventional electronic processing systems. Bioelectronic devices can be used to establish a bidirectional communication path with living systems. They can be used to regulate the physiology of cells, tissues, and organs in a chemically specific manner. In addition, they can also be applied to living systems to selectively sense, record, and monitor different signals and physiological states, as well as convert relevant parameters into electronic readout for further processing and decision making. Relevant contributions recently achieved by our research group are:

-Development of ultra-sensitive devices to measure electrophysiological signals with amplitudes below 1 V. The methodology has been successfully used to measure faint and slow oscillations produced by non-electrogenic cells (glioma and astrocytes).

- Recording of AM and FM signal patterns in populations of neural cells

Recent publications in Bioelectronics

Mestre, A. L. G., Cerquido, M., Inácio, P. M. C., Asgarifar, S., Lourenço, A. S., Cristiano, M. L. S., et al. (2017a). Ultrasensitive gold micro-structured electrodes enabling the detection of extra-cellular long-lasting potentials in astrocytes populations, Scientific Reports 7 (1), 14284, 1-11.

Pedro M. C. Inácio et al., Bioelectrical Signal Detection Using Conducting Polymer Electrodes and the Displacement Current Method, IEEE Sensors Journal, 17, 13 (2017 )

Mestre, A. L. G., Inácio, P. M. C., Elamine, Y., Asgarifar, S., Lourenço, A. S., Cristiano, M. L. S., et al. (2017b). Extracellular Electrophysiological Measurements of Cooperative Signals in Astrocytes Populations. Front. Neural Circuits 11, 1-9.